The prawns of the genus Macrobrachium with economic and fishing interest are well known and exploited in almost all coastal communities in Latin America. However they have not been properly studied and their conservation is at risk. The economic, social and cultural characteristics in most countries in the region have resulted in habitat degradation and overfishing, consequently, the populations of this genus of aquatic macro invertebrates are endangered. From this, it follows that all these are poorly studied, and their population status is not known, although in the case of M. amazonicum there are numerous studies. Culture techniques is the area in which more reasearch hs been done. This paper summarizes the knowledge we have on native species of Macrobrachium in Latin America and discusses their economic importance and conservation. conservation.